Changing the content of testosterone in human blood can be an indicator of a number of different diseases.
When interpreting blood test data for testosterone, the physician takes into account not only the results of the analysis, but also the data of the anamnesis, patient complaints and the results of the medical examination. Often changes in the amount of this hormone are detected in the following cases.
High levels of testosterone in men can be caused by testicular or adrenal cancers.
In boys under 10, a high testosterone level may indicate early onset of puberty, testicular tumors, or adrenal pathology.
High numbers of testosterone in women may be associated with ovarian or adrenal cancers, as well as polycystic ovary syndrome (PCOS).
Low testosterone values in juvenile pubescents signal the problems of testicular functioning such as slow development, damage, or testicular atrophy. This can also be the result of treating estrogen-containing drugs. In addition, low levels of testosterone may be a sign of some congenital or acquired illnesses (such as Down syndrome, Kleinfelter syndrome, liver cirrhosis). Chronic alcohol use can also result in low levels of this hormone.
In women, low testosterone levels can be caused by pituitary pathology, Addison's disease, loss of ovarian function (after illness or surgery), and some drug therapy (eg, glucocorticoids or estrogens).
What can affect the results of the study
Some factors can affect the reliability of the study. These include many medicines (such as birth control pills, glucocorticoids, barbiturates, etc.), Prostate Cancer Therapy. The presence of hyperthyroidism may increase the amount of protein-carrier for sex hormones, and hypothyroidism - reduce.
Things to think about
Much of testosterone in human blood is associated with carrier protein, which increases with hyperthyroidism and obesity. It is necessary to check the amount of other hormones in the blood such as follicle stimulating hormone (FSH) or luteinizing hormone (LH) to determine that the pathology is in the ovaries or testicles and not in the pituitary gland. High levels of LH and low testosterone numbers indicate that the testes or ovaries are not working properly. Low concentration of LH and very low or high values of testosterone - a possible feature of the pathology of the pituitary gland.
Hormonal estrogen therapy in postmenopausal women is also able to lower testosterone concentrations.