Treatment for parkinson's disease

Medications For The Treatment Of Parkinson'S Disease (Health And Medical Video July 2018).

In the etiology and pathogenesis of Parkinson's disease, many remain obscure, but the successes achieved in recent years in the study of the disease, give rise to high hopes. What are the methods for treating Parkinson's disease?

Chronic progressive disease of the central nervous system with characteristic disorders of motor function was first described as "trembling paralysis" two hundred years ago by English physician J. Parkinson. Today it is one of the most common nerve diseases, it is called Parkinson's disease, or Parkinson's disease.

A patient with Parkinson's disease has problems with motor function. Ordinary movements that are common to a healthy person become impossible, there is a constant tremor of the hands and feet, the face resembles a mask due to lack of facial expressions. Possible salivation, increased tone of all muscles, overall stiffness and slowness of movements (in particular, slow motion in small steps), loss of balance in standing position and walking.

Violations of arbitrary movements occur as a result of the defeat of certain nerve cells of the brain producing dopamine (dopamine). It is Dopamine that sends signals to the part of the brain that controls the movement, this makes the muscles obedient and allows them to smoothly shrink. In the event of a lack of dopamine, this does not occur and there is a violation of motor functions: there are difficulties in managing their own movements.

Possible causes of parkinsonism

Why do dying dopamine producing nerve cells is unknown? In almost half of cases, the cause of the disease can not be established. For possible reasons, called aging, bad ecology. In some people, the most likely cause of this disease is pathologically altered genes.

In search of a solution

Parkinson's disease is incurable, therapy reduces symptoms and improves the quality of life. If the symptoms are expressed insignificantly, then the treatment will not be needed until the condition of the patient begins to increase and interfere with everyday life.

However, this moment will still come, because Parkinsonism - the disease is progressing, but nobody knows how quickly the disease will develop in each particular case.

Many people live for years with one minor symptom (for example, tremor in one hand). If necessary, the doctor may prescribe one or more medicines - to achieve a better result.

Treatment for Parkinson's disease: drug therapy

Some drugs used today to treat parkinsonism simulate dopamine, others block its destruction.

Many of them help in the early stages of the disease, but with prolonged intake cause side effects, greatly complicate further life.

The long-term use of some anti-Parkinsonian drugs gradually erases their uniform effect during the day. For example, the prescribed single dose begins to act after some time (30-40 minutes) - the patient "switched on", and after a couple of hours the drug stops acting and comes "shutdown" with such a decrease in motor activity that the patient freezes for a few minutes and can not move. From the place.

Sometimes such episodes of "hardening" can last for hours and even days - the neuroscientists call them akinetic crises. Hospitalization may be required to withdraw a patient from such a condition: the patient will need intravenous drip infusions and probe feeding.

Antiparkinsonian funds are used worldwide for over 30 years, and the experience shows that symptomatic unable to fundamentally solve the problem.

The search for new treatments for Parkinson's disease, which could slow down the degenerative process in the brain are being increasingly recent years, but so far they have failed.

Today, while there is no clear understanding of the cellular mechanisms of the degenerative process in this disease, new alternative approaches to the treatment of Parkinson's disease are needed.

Treatment of Parkinson's disease: stimulation of deep structures of the brain

Almost a hundred years ago it was discovered that the destruction of a small number of brain cells responsible for abnormal motor activity reduces tremor (trembling of the limbs).

This discovery was taken on board, and there was a new kind of treatment - deep brain stimulation. The essence of the method is that the surgeon conducts an operation for locating the electrodes in the patient's brain.

Electrodes transmit small electrical signals to certain areas of the brain that control movement and improve their work.

Once this method, developers have reported that such stimulation leads to a significant decrease tremor and rigidity, the method was the one of the first places in the treatment of Parkinson's disease. Sometimes, on the background of stimulation, it was possible to significantly reduce the dose of drugs and generally do without them. However, stimulation of deep brain structures can stop the disease process and does not solve the problems associated with loss of cognitive (cognitive) function, speech disorders and sense of balance.

Electro vascular therapy for the treatment of Parkinson's disease

Electro vascular therapy causes a significant increase in the concentration of dopamine that is absent in patients with Parkinson's disease.

After a convulsive attack, a strong antiparkinsonian action quickly occurs, stiffness (a functional state of skeletal muscles characterized by a sharp increase in their tone and resistance to deforming efforts) and other symptoms of the disease decrease.

In parallel, electroconvulsive therapy has a pronounced antidepressant and antipsychotic effect.

New Approaches to Parkinson's Disease Treatment

In addition to stimulation of the brain and ECT, the possibility of replacing dead cells with new transplantation is considered. However, it is not yet known whether the transplantation will give a proper effect.

Bed is the enemy of the parkinsonika

In addition to drug therapy, patients with parkinsonism show massage and therapeutic physical training, nootropic drugs, vitamin complexes and diet. Such patients need to move as much as possible, make a charge, perform some simple tasks - in a word, constantly motivates the stimulus to act.

The combination of traditional medical methods of treatment and new approaches, attention and care from relatives will undoubtedly facilitate the condition of many patients and help prevent the progression of painful illness.

Treatment for parkinson's disease

Category Of Medical Issues: Diseases

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