What provokes the development of colorectal cancer.
About a quarter of people over 50 have at least one polyp in the colorectal intestine. Most cases of colon cancer develop from polyps that are formed from glandular intestinal tissue. In general, polyps are benign, but often their zlokochezstvlenya occurs.
The exact causes of colon cancer are unknown. However, there are a number of risk factors for the development of this disease.
Colon cancer is largely associated with a number of other diseases. High-risk individuals include people with a history of a family history or a history of polyps in the colon, inflammations such as nonspecific ulcerative colitis, Crohn's disease, and pancreatic cancer, breast cancer, ovaries, or uterus.
The development of colon cancer contributes to genetic predisposition.
There are hereditary diseases that dramatically increase the risk of its development: family adenomatous polyposis; Polyps linked to the MYH gene; Gardner syndrome; Turkot's syndrome; Pitts-Egers syndrome; Juvenile polyposis, caudo disease. For these diseases characterized by the formation of multiple polyps in the intestine, which can be zlokachestvlyatsya.
Hereditary non-polyposis colon cancer - the most common form of colorectal cancer, also known as Lynch syndrome. The disease is associated with other forms of cancer, such as endometrial cancer, small intestine, urinary tract, urinary bladder, ovaries, stomach, bile ducts, skin and some types of pancreatic cancer.
Also, to some extent, it is associated with the risk of developing colon cancer, although the cause-effect relationship between them has not yet been established.
People in whose diet a large number of vegetables and fruits are present are less likely to develop this type of cancer. Some studies have shown that animal fat and protein contribute to the development of colon cancer, others have not found any connection between them. Some scientists believe that fat is the main cause, while others are accused of protein. Others argue that the main cause is neither fat nor protein in themselves, but a way of cooking. The fact is that at high temperatures of processing of fat and protein, especially during frying, potentially carcinogenic substances that lead to the development of cancer are produced.
Influence of certain chemicals
Chlorine, which in small quantities is commonly used to purify drinking water, may increase the risk of developing colon cancer.
It was noticed that contact with asbestos, indole, scalpel also increases the risk of developing this type of cancer.
This virus is sexually transmitted and causes the formation of papillomas that can be zlokachestvlyatsya. The presence of this virus increases the risk of developing cancer of the rectum.
Surgical intervention in history
For example, ureterosigmostomy (after the removal of the bladder) and cholecystectomy (removal of the gallbladder). However, some studies suggest a connection between surgical intervention and the risk of developing cancer, others are not.
Colon cancer in the history
If the patient had previously had colon cancer, that is, the probability of recurrence of the disease, especially if the first case was diagnosed before age 60.
Smoking and alcohol abuse increase the risk of developing colon cancer.
People whose close relatives have had cancer of the colon are at high risk. The risk increases if the cancer has been detected in more than one close relative.
Exposure to radiation
Radioactive exposure increases the risk of developing cancer, but only on the affected tissue.