Analysis of saliva predicts cancer

Delta Dental Salivary Diagnostics (Health And Medical Video July 2018).

The pancreas is an organ of the digestive system, which is located behind the stomach in the abdominal cavity, in the left hypochondrium. The gland produces enzymes involved in digestion, and special hormones that support normal blood sugar levels (insulin and glucagon).

Pancreatic cancer

Pancreatic cancer is one of the most formidable and dangerous oncological diseases. The symptoms of cancer are nonspecific and blurred and often appear only in the later stages of the disease, when the tumor has already begun to spread. In this connection, the diagnosis of cancer is often delayed, which makes the treatment ineffective and worsens the prognosis for the patient's life.

Survival in this tumor is very low: in the absence of timely treatment within five years after the discovery of a tumor, up to 95% of patients die.

Analysis of saliva can help diagnose pancreatic cancer

The situation is complicated by the fact that there are no reliable tests that would reveal the disease at an early stage. However, according to research by scientists from the Medical School of the University of California (Los Angeles, USA), such an examination may well appear shortly.

Specialists have found that the saliva of people with pancreatic cancer has certain features of the microbial composition.

Early diagnosis of pancreatic cancer

According to scientists, deviations in saliva appear not only in pancreatic cancer in the early stages, but also at the smallest pre-tumor changes.

Researchers have studied the bacterial salivation of healthy people and cancer patients. The obtained data were compared with the results of analyzes in chronic pancreatitis - inflammation of the pancreas, which often leads to cancer.

Composition of the saliva of patients with cancer

It turned out that in the saliva of patients with cancer patients are found to be much more bacteria of the species Granulicatellaadjacens, which in healthy people are almost not detected. At the same time, two other types of bacteria (Neisseriae longata and Streptococcus mitis) were virtually absent in inflammation and pancreatic cancer in saliva.

Scientists have not yet found out whether the deviation in the composition of the microflora is only a reflection of the occurrence of cancer changes or serves as their cause. However, research suggests that colonization of the oral cavity by unusual types of bacteria or microbiocenosis can quite provoke tumor changes.

It has long been known that gum disease contributes to the development of certain diseases. Oral infections are often combined with common inflammatory processes, as well as with certain types of malignant neoplasms, heart attacks, stroke and diabetes mellitus.

Results of experiments

The work of American scientists is just the first step in the long process of developing a really effective early detection program for pancreatic cancer.

Finding the only simple diagnostic test for this disease is practically impossible. Analysis of saliva will only help identify a group of people who have a high risk of developing cancer. However, for accurate diagnosis, other tests, including blood tests, endoscopic techniques and visualization of the organ (ultrasound, CT, or MRI) are needed.

The data obtained during the study, scientists presented in the international journal on gastrointestinal diseases Gut.

Analysis of saliva predicts cancer

Category Of Medical Issues: Diseases

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