Non-hodzhinki lymph

Lymphatic System: Crash Course A&P #44 (Health And Medical Video July 2018).

Treatment of non-Hodgkin's lymphoma and its outcome largely depends on the subtype of lymphoma.

Non-Hodgkin's lymphoma (lymphosarcoma) is a group of tumor diseases occurring from cells of the lymphatic (immune) system.

The stage of cell differentiation, that is, the process of implementing a genetically determined program for the formation of a specialized phenotype (a combination of characteristics) of the cells from which the tumor forms, and the nature of the growth of this tumor inside the involved lymph node - all this determines the clinical features of the disease and the prognosis.

Annually in the world of non-Hodgkin's lymphoma more than 300 thousand die. The incidence of this form of cancer grows very rapidly, by 4-8% per year.

For an unknown reason, non-Hodgkin's lymphoma often affects men than women. With age, the probability of a disease increases. At the rate of its spread this pathology occupies the third place.

Today, about 40 subtypes of non-Hodgkin's lymph have been isolated on the basis of oncohematology, depending on which the prognosis can be very good (survival of 10-20 years) and extremely unfavorable (survival less than a year).

Non-Hodgkin's lymph: reasons

Despite the fact that medicine has taken a step far forward, the cause of lymphoma is still unknown.

It is certain that only non-Hodgkin's lymphomas are contagious and develop very quickly.

According to one of the theories, the cause of the growth of abnormal cells may be infectious diseases. Among the risk factors are traditionally considered (only considered!) Ionizing radiation, carcinogens, deterioration of the environment.

Often tumor cells inhibit the development of similar normal cells and cause an immunodeficiency state. Often, when lymphomas are detected, various abnormalities of the chromosomal apparatus of the cell (genetic material).

Most often the tumor develops when combined with several causative factors. Also, this kind of lymphoma may occur when taking medications that suppress the activity of the immune system, as is done for subsequent organ transplantation.

Degree of aggression by non-Hodgkin's lymph

Some types of non-Hodgkin's lymphomas take place slowly and favorably, for a long time do not require special treatment - they are called indolent.

For others, on the contrary, is characterized by rapid development with a large number of symptoms, requiring the immediate start of treatment. Such lymphomas are called aggressive. There are lymphomas with intermediate characteristics. Since lymph is a tissue that is present throughout the body, some types of lymph are affected by organs and tissues, but without damage to the lymph nodes. Such lymphomas are called extranodal.

Non-Hodgkin's lymph: diagnosis

Confirm or deny the presence of non-Hodgkin's lymphoma can be by biopsy - one of the most reliable diagnostic methods. This is probably the most reliable way to diagnose.

Ideally, the histopathological study should be complemented by immunohistochemical, as well as a whole set of clinical examination methods with mandatory blood analysis on oncomarkers.

Only the use of an integrated approach in diagnosis can provide confirmation of the diagnosis and, accordingly, pick up competent therapy for the patient, capable to bring the maximum effect.

Treating or not treating non-Hodgkin's lymph

The treatment program, as a rule, depends on the type of lymphoma and the condition of the patient. As already mentioned above, indolent lymphomas may not require treatment, observing a physician (hematologist or oncologist) is sufficient.

The emergence of the first signs of lymphoma progression, such as an increase in lymph nodes, increased weakness, increased night sweats and fever, is a signal for the beginning of treatment.

In locally advanced stages, lymph nodes affected by tumors are often used. In generalized stages, a more effective method is chemotherapy, and radiotherapy is used to fix the effect of chemotherapy.

The spectrum of possible medications for the treatment of indolent lymphomas is quite large: the use of monoclonal drugs has opened a new era in the treatment of tumors.

Monoclonal antibodies - substances, each of which attacks a certain purpose. The selective receipt of the drug directly into the tumor and the directed effect on it can significantly reduce the side effect on normal cells and maximize the therapeutic effect of the drug.

Complete treatment for indolent lymphomas is unlikely today, the main purpose of treatment is to increase the duration and improve the quality of life of the patient.

Unlike indolent, aggressive lymphomas require immediate onset of treatment. The purpose of treating aggressive and highly aggressive lymphomas is to treat, but this is not possible in all cases.

If the bone marrow is not impressed, then there is a good possibility of intensive chemotherapy with subsequent transplantation of the autologous (own) bone marrow, prepared in advance from the patient prior to intensive care. In the presence of certain conditions, the allogeneic (from the donor) bone marrow transplantation is used.

Side effects of radiation and chemotherapy can be quite serious, such as fatigue, fatigue, nausea and vomiting, pain, hair loss, various infectious complications, blood clotting disorders, bleeding and many others, but in most cases they are temporary in nature..

Alternative methods of treatment of non-Hodgkin's lymph

The benefits of grass, shark cartilage, homeopathy and other alternative therapies in the fight against lymphoma are still not proven.

Intervention of non-traditional methods (and such proposals - a lot) can reduce the chances of success, and in combination with chemotherapeutic drugs and cause irreparable harm at all.

The safest is the treatment chosen by a specialist, and since lymphoma can be life-threatening illness, it is not worth taking risks and experimenting with your own health.

If you still decide to seek alternative medicine (herbal medicine or homeopathy) in addition to already prescribed treatments, first, inform your doctor, and secondly, use information that contains the results of scientific research, Devoted to these methods.

Non-hodzhinki lymph

Category Of Medical Issues: Diseases

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