Baset's disease, which was first described in detail by the German physician Karl Adolf von Basetov in 1840, refers to diseases of the endocrine system associated with increased production of hormones of the thyroid gland.
It is accompanied by an increase in the volume of the gland (the formation of goiter) and a violation of the work of almost all systems of the body (thyrotoxicosis).
The main causes of cerebellar disease
According to the latest data, most autoimmune processes are based on the hereditary predisposition, the negative influence of environmental factors, the effects of stress, hormonal adjustment, such as during pregnancy or during the onset of climax, and other factors, which are the basis of this disease.
The most prone to the disease is a woman of childbearing age (80-85% of cases), but bazedova disease is found in women over 50-55 years, as well as in adolescents. Men rarely suffer from different age groups (in 12-13% of cases).
In some cases, a factor in the development of diffuse thyrotoxicosis are other disorders of the functioning of the endocrine system (diabetes mellitus, hypoparathyroidism, pituitary disease), viral diseases, radiation (for example, radiation therapy, excessive insolation), the influence of some pharmacological agents (radioisotope iodine, etc.).
Symptoms of Cerebral Disease
Perhaps both acute and gradual occurrence of symptoms of the disease. At the same time, in the first place surrounding people notice:
- An increase in the size of the eyeballs in the patient, which is due to the appearance of exophthalmos;
- Increased nervousness, fussiness, emotional lability;
- Increase in neck volume (goiter).
Patients themselves are concerned about the following symptoms:
- Tachycardia and arrhythmia;
- Increased anxiety
- Disturbance of concentration;
- Sleep disturbance;
- Trembling in the limbs;
- Hyperhidrosis (increased sweating);
- Muscle weakness;
Other symptoms of cerebellar syndrome are possible:
- Enhancement of pigmentation of the eyelids;
- incomplete eyelid closure, leading to the onset of symptoms of conjunctivitis, corneal lesion, the development of glaucoma, visual impairment;
- in severe cases may develop degenerative changes in the myocardium, the emergence of heart failure, pulmonary edema;
- In women there is a violation of the menstrual cycle, the development of infertility.
Complications of Graves' disease in a thyrotoxic crisis occurs with marked hyperthyroidism and is accompanied by symptoms of increased excitability, hallucinations appearance, a sharp increase metabolism and internal organs (raising the temperature to 41-42 ° C, tachycardia, diarrhea, development of jaundice and other symptoms of toxicity).
Thyrotoxic crisis can go into a coma, followed by death. May provoke crises infections, severe stress, trauma, surgery, lack of adequate treatment for hyperthyroidism.
Diagnosis of cerebellar disease
In the diagnosis of cerebellar disease, the following methods are used:
- Research of thyroid function by radioisotope scintigraphy, determination of iodine level, thyroid gland and thyroid hormones in the blood;
- Carrying out biochemical studies of blood (determination of bilirubin, cholesterol, protein, liver enzymes and other indicators);
- Ultrasound, MRI of the thyroid gland and other internal organs, ECG;
- Advanced neuro-ophthalmological examination and consultations of related specialists (cardiologist, neurologist, gynecologist, etc.).
Treatment of Cerebral Disease: Basic Principles
In the treatment of cerebellar disease, a combination of one or several types of treatment is possible: medicamentous (anti-thyroid drugs), surgical (resection of the gland), radiation (use of radioisotope iodine), the goal of which is the optimal correction of hormonal status.
Simultaneously, symptomatic therapy aimed at improving the functioning of the cardiovascular system, the central nervous system, normalization of sleep and the functioning of the digestive system are performed. Of great importance is a high-grade nutrition, rich in vitamins, minerals, and proteins.
Treatment of thyrotoxic crisis is carried out in the hospital in the intensive care unit.