Candidiasis of the intestine is the penetration of the mucous membranes of the genus Candida. To a large extent this is facilitated by the administration of antibiotics and inhibition of healthy intestinal microflora.
The intestinal candidiasis has a tendency to a chronic and relapsing course, therefore its first cases of disease require complex therapy, based on accurate diagnosis and individual selection of treatment regimens. Only in this case can be expected recovery of healthy intestinal microflora.
Diagnosis of intestinal candidiasis
- In order to effectively treat intestinal candidiasis, it is necessary to determine the exact type of Candida fungus, since different strains are susceptible to various antifungal agents. In addition, it is necessary to determine the individual sensitivity of isolated strains of fungi to antimycotic drugs.
- The most reliable method of diagnosis of candidiasis is the detection of a fungus in the study of fluids and tissues of the body, which normally should be sterile (for example, in synovial fluid from the cavity of joints, in the intestinal tissue during their biopsy, etc.)
- Serological studies using which determine the level of blood serum content of antibodies to fungi. However, only the doctor should evaluate the data obtained, since even a positive result may be a sign of carriage in individuals who once became ill with candidiasis or with impaired immunity.
- Bacteriological examination of feces allows us to determine whether there are pathogenic bacteria (pathogens of intestinal infections) in the human organism. Normally, the number of fungi of the genus Candida must not exceed more than 10 ECU/g.
- Fibrocolonoscopy allows you to visually assess the condition of the intestine, conduct a biopsy for microscopic examination. With the help of the endoscope, it is possible to collect feces from different parts of the intestine to carry out a more accurate analysis of the composition of the microflora.
Treatment of intestinal candidiasis
It is now established that for the treatment of intestinal candidiasis, it is necessary to use medicinal products not absorbed from the intestinal cavity. To drugs of this type include nystatin, levorin, pimafucin. But they should be prescribed only by the doctor in a specific dosage and with the control over the effectiveness of therapy, as sometimes in patients during the treatment may develop allergies, dyspeptic phenomena.
Pimafucin is considered an effective antifungal drug, and until now, the development of microorganisms to it is not a privilege. It is allowed to be used for the treatment of women during pregnancy and lactation, as well as newborns and children. But during the first two days of tablet administration, abdominal discomfort, dyspepsia (podatashovaniya, diarrhea), which gradually disappear within a few days, may occur. Treatment of candidiasis in the intestines of Pimafutsin is prolonged, up to 2 years.
To prevent the development of a generalized form of candidiasis, it is desirable to add local therapy to medical therapy. These may be rectal candles, vaginal suppositories. Often the treatment of intestinal candidiasis is carried out simultaneously with the treatment of concomitant diseases, with immunodeficiency states: in AIDS, tuberculosis, in the treatment of patients who have passed the radiation or chemotherapy.
Criteria for cure - a negative analysis of sowing on fungal cultures, as well as the disappearance of symptoms of intestinal candidiasis. But in some cases, repeated courses of antimycotic treatment are recommended to obtain a lasting effect.
Additional therapy for intestinal candidiasis
Additionally, symptomatic therapy is performed. For the treatment of intestinal candidiasis, the following groups of drugs are used:
- Antispasmodics (no-spas, spasmolgon, spasmomen, duspatalin, meteospazmil);
- Antidiarrhea (imodium, debridate, calcium carbonate powders);
- Laxatives (guttalaks, bisacodyl, regulalax);
- Adsorbents (activated charcoal, carboline, carbolong, polyfepan, smecta, kaolin, cholestiramine, bilinean);
- May poly-enzymes and other preparations that improve digestion (pancitrate, creon, panzinorm, festal, triferment, mesim-forte, essentiale, legalon, karsil, etc.);
- Drugs that increase immunity (immunomodulators or adaptogens: extracts of ginseng, eleutherococcus, levensee, echinacea, magnolia, pantocrine, as well as thymogen, thymalin levamisole, reaferon, leukinferon, lipopid, and others);
- Antiallergic drugs (suprastin, tavegil, pylophen, fenkarol);
- Multivitamin (yunikap, center, vitrum, duvit, etc.);
- Antioxidants (vitamins A, E, C, oleifene, amtizol, gutimin, Trimino, etc.);
- Drugs that reduce flatulence (meteospazmil, espumizan, dysflavitol);
- Anti-anemic drugs of iron with iron deficiency anemia (ferroplex, ferrogradum, konferon, ferrumkl, ferrofolgamma), and when vitamin B12 deficiency anemia is injected intramuscularly with vitamin B12.
Prevention of intestinal candidiasis is to minimize the factors that provoke the development of dysbiosis, to a timely visit by a specialist when the first symptoms occur, to a balanced and balanced diet, and treatment of the underlying disease that provoked candidiasis.