Aspirin bronchial asthma occurs in 9-22% of cases of bronchial asthma, more often the disease develops in women.
Bronchial asthma rightly stands in line with the most severe diseases of the respiratory system. Along with chronic inflammation of the airway mucus in patients with bronchial asthma, coughing, dyspnea, attacks of strangulation, and nasty sensations in the chest cavity are also observed.
Causes such phenomena bronchospasm - narrowing of the bronchi, caused by the contraction of the muscles, as a result of which the air improperly passes through the bronchial tree. Usually, the patient can breathe easily, but in order to breathe out, it is necessary to make significant efforts.
Aspirin Asthma: Bronchospasm from Drugs
If the use of nonsteroidal anti-inflammatory drugs leads to bronchospasm, then such a clinical course of bronchial asthma is called aspirin asthma. Medicinal products that lead to the development of aspirin asthma also include ibuprofen, ketoprofen, diclofenac, piroxicam, indomethacin, and others.
In most cases, this disease begins with a normal but prolonged cold. Such prolonged rhinitis as a result can lead to rhinosinusitis of polyposis.
The patient in this case complains of severe nasal congestion, headache, pain in the zone of paranasal sinuses, mucous discharge from the nose. When receiving nonsteroidal anti-inflammatory drugs in half of the patients there are attacks of breathlessness.
In the patient's body, leukotrienes are activated. These are special substances that are involved in the development of inflammatory reactions, so-called inflammatory mediators. Leukotrienes cause a reduction in smooth muscle of the bronchi, a change in their secretory function and swelling of the bronchial mucosa.
Diagnosis and treatment
This disease is diagnosed as a result of detection in the nasal cavity and in the washing waters of the bronchi, as well as in the urine of leukotrienes.
Thanks to modern medical achievements, scientists have created a new type of anti-asthma drugs that are antagonists of leukotriene receptors. The use of drugs of this group, for example Zafirulkasta, With aspirin asthma gives a positive effect.
It should also completely exclude the use of tartrazine, a yellow dye. Tartrazine has a chemical structure similar to aspirin. Patients should not take any yellow medications or preparations covered with a yellow coating. If foods contain sulfites, benzoates or tartrazine, they should also not be consumed in food.
With aspirin asthma it is recommended to avoid foods containing industrial or natural salicylates. These are canned food, ham, sausages, raspberries, black currants, plum, apricots, tomatoes, oranges, cherries, cucumbers.
Tartrazine is a part of muffins, cakes, cakes and yellow cream, low alcohol drinks, sweets, pills.