Defeat of joints occurs in 75% of patients with acromegaly and has its characteristic features.
Acromegaly is a rare pathological condition due to excessive pituitary growth hormone production (usually associated with pituitary adenoma), manifested in the form of proliferation of bone and cartilage tissue, as well as the development of fibrosis in the articular tissues.
The main manifestations of arthropathy in acromegaly
- Changes are observed in almost all joints of the limbs, as well as in the cervical and lumbar-sacral parts of the spine. One of the most common signs of acromegaly is pronounced deforming osteoarthritis, accompanied by rash in the joints, compaction of periaryticular tissues, an increase in the volume of articular bags.
- Increase of the volume of fingers, often with deformation in the form of "drum sticks", increase of additional, sesamodic stones and peripheral parts of bones (lower jaw, heel bones, nail phalanges), as well as increased propensity to form limb osteophytes in places where they are fixed to them Tendons and ligaments.
- The spine in patients with acromegaly deforms mainly due to increased chest kyphosis and lumbar lordosis, scoliosis, which is associated with a violation of the bone structure and an increase in the volume of vertebral bodies. Simultaneously, there is a restriction of the mobility of the ribs in the breathing and the formation of the barrel-like shape of the chest.
- Often in patients there is a syndrome of the carpal tunnel associated with an uneven increase in the volume of para-articular tissues and bones in the area of the radiopaque joint.
- Very often, patients are concerned about muscle pains, combined with an increase in their size and increasing weakness, and 1/3 of all patients are diagnosed with Raynaud's syndrome (periodically there is spasm of peripheral arterial vessels, accompanied by painful manifestations in the area of impaired blood supply).
Diagnosis of arthropathy in acromegaly
Often, the doctor makes a preliminary diagnosis based on the appearance of the patient, but in cases where acromegaly only begins to develop, for example, when the pituitary adenoma begins to grow, diagnosis is quite complicated.
Certain role in correct diagnosis is played by X-ray examination, which reveals characteristic changes in the structure of bones and joints: