Usually, the disease occurs suddenly on the background of complete well-being in the form of acute pain in the abdomen or in the chest, pain in the joints with an increase in body temperature. The first attacks last no more than two days, but over time their duration may increase.
Sometimes, lesions of the joints are only pain, but may be accompanied by the appearance of edema. In most cases, these are asymmetric joints of the lower extremities, and rarely - the joints of the brush. Swelling of the joints rapidly increases and quickly disappears, but with time it is possible to maintain the pain.
In cases where the first one is affected by the hip joints, as well as abdominal pain, fever, lumbar or chest pain, the diagnosis of the disease is difficult, and patients can be hospitalized in a surgical or therapeutic department. In the same period, at least - after exacerbation, the patient shows the appearance of stiffness in the joints and the appearance of rash on the skin around them, the blisters and small subcutaneous nodules, more often - on the lower extremities. These changes can last for 3-7 days and then completely disappear in almost all joints, except for the hip. With prolonged existence of the disease osteoporosis and deforming osteoarthritis develops.
Diagnosis of joints damage during periodic illness
- Outside the exacerbation and during the first exacerbations of X-ray changes can not be found. However, at later stages of the illness, during the X-ray examination, signs of sacroilitis, koxit (inflammation of the hip joints) are possible on the background of osteoporosis, later degenerative-dystrophic changes (deforming osteoarthritis) are detected in them.
- When conducting an ultrasound of the joints in the acute period, manifestations of bursitis, synovitis, and the presence of effusion in the joint cavity can be determined.
- In peripheral blood during the exacerbation leukocytosis, elevated ESR, increased serum and fibrinogen, the rheumatoid factor is not determined.
- Urinalysis is often unchanged until the kidneys are involved in the process. Later it can detect amyloid.
Basic principles of treatment of arthropathy with periodic illness
Treatment is mostly symptomatic, but recently, long-lasting treatment with colchicine (or colchamine) has been shown to be the most effective treatment with a maintenance dose. The use of corticosteroids is ineffective.
For pain relief in the acute period, analgesics, non-steroidal anti-inflammatory drugs, including ointments, gels, compresses for sick joints, and also antipyretic, phytotherapy (locally and internally) are prescribed. A good effect is given by physiotherapy, reflexology, osteopathy, and after exacerbation - spa treatment.