High bilirubin: causes

What Does High Bilirubin Levels Signify In Lft? - Dr. Sharat Honnatti (Health And Medical Video 2018).

The causes of high bilirubin in the blood are only two: increased destruction of red blood cells or the difficulty of processing and eliminating bilirubin with bile.

The simplified scheme of education of bilirubin is as follows: erythrocytes after the end of their life are destroyed and release hemoglobin, from which after a series of chemical reactions, bilirubin is formed. Most often it occurs in the liver, spleen and bone marrow.

High bilirubin: diagnosis

The content of bilirubin in the blood is called bilirubinemia, it is determined by biochemical analysis of blood (taken from the vein). To obtain the most reliable and accurate result blood should be given in the morning and strictly on an empty stomach.

The bilirubin contained in the blood is subdivided into three types:

  1. Direct (connected, conjugated), norm - up to 4.3 μmol/l;
  2. Indirect (free, unconjugated), norm - up to 17,1 micromoles/liter;
  3. Total (it consists of fractions of direct and indirect bilirubin), the norm - 8,5 - 20,5 micromoles/liter.

Causes of bilirubin increase

The main reasons for increasing bilirubin in the blood are as follows:

High bilirubin: causes

Category Of Medical Issues: Diseases